After a strange incident with the Tree of Harmony, the Mane 6 are transported to another dimension of where each pony was turned into a human version of themselves with no idea how they ended up there or how to get back. This is Pinkie's Adventure...

The Adventures of the Mane 6 during season 6, with some extra characters.

A young boy in Orlando, Florida gets four lost girls guests to his house until they can find a way home, which happens to be in Equestria from My Little Pony: Friendship is Magic.

After a tragic accident with a couple parents, a young boy and his baby sister try to run away, and nearly get severely hurt. But it was up to one pony to make a tough decision when the two human children came to Equestria.

Twilight Sparkle, along with her five closest friends, her family, the Cutie Mark Crusaders, and two of her Mobian friends accidentally end up back in the past, the time where their Mobian friends originally came from.

An orphan boy who has been living in an orphanage his whole life has been given a chance to have a home, but things get a little edgy when he wakes up, not just as a pony, but of a pony in the opposite gender.

A human boy who has been abused by his terrible aunt and uncle has somehow ended up in Equestria as a Pegasus, and taken in by Rainbow Dash.

The human child of Princess Twilight Sparkle gets a visit from an unexpected friend from his who was from another world.

Rainbow Dash comes to the real world, where MLP hasn't happened, she helps a teenage boy when he is having trouble at his school by bullies and a principal that thinks he is nothing but trouble.