The process and results of experimentation can be problematic or dangerous in terms of safety and disposal. Thanks to the convenience of dimensional portals, however, problematic and dangerous experiments can be easily dealt with.

When Discord gets turned into stone the second time around, the Tree of Harmony, now older and far more developed, takes the opportunity to reform him.

Anon's immune system wasn't prepared for the various maladies found in Equestria and nearly perishes. He eventually gets to choose how to move forward while a way home is found, although nothing's ideal.

Twilight Sparkle has been experimenting with ways of spreading friendship. One such way is by using music.

A human discovers a strange book in a library, where an animated, purple pony appears on every page with the purpose of teaching friendship and solving friendship problems.

Luna gives Celestia an outlet to be herself, since appearances were so important to her sister's portion of their duties.

Marshall is in a rut, drifting without a purpose. Rarity is in a rut, looking for inspiration. By chance they meet, despite living in different universes, and find what they're yearning for with the aid of the other.

Pinkie Pie has been aware of the audience watching her world and its ponies, and now she has the time and opportunity to throw parties for said audience. And sometimes she comes bearing gifts.

Derpy is a special pony who has a talent for traveling between universes. Today, she adds an extra dimension to her life.

Luna takes a trip to familiarize herself with Equestria's advancements, as well as places that had not been settled a millennium ago, and discovers something that requires an explanation from her sister.

Before going to Ponyville, Twilight Sparkle connects more dots than usual, which gives her more reason to face Nightmare Moon alone. (Pamphile (PAM-feh-lee) means "friend of all" in Greek.)