The Doctor has just regenerated into his eleventh incarnation, and upon his arrival he meets a new pony to call a friend. A heartbroken mare. But before he is able make a proper introduction, they learn of a new threat to the small town of Ponyville. Citizens are disappearing left and right with no evidence as to where they've gone or who ( or what took them). It's up to the mad doctor and his new friend to unravel the mystery.