The not-too-distant future: After the Thousand Years Argument and the banishment of the creature who became Nightmare Moon, it has fallen to the unicorns of Equestria to once again raise and lower the moon as they did in ancient times. But magic power is in short supply, and it's only with the aid of Hydrate, an expensive and addictive magical supplement, that most unicorns are able to contribute to the cause without burning out their powers completely. For those who aren't able (or rich enough) to pull their weight, their fate is to be hunted by Midnight, a necessary evil of Celestia who drains ponies dry to give their energy to those better able to ensure a safe and stable orbit. Amidst this climate of corruption and addiction, a sheltered and magicless filly named Sweetie Belle must venture forth to discover the secret behind her mysterious disease and her adoptive mother's true nature...

A crossover/parody of Repo! The Genetic Opera, born when a sick and grumpy author suddenly remembered that he was allowed to write whatever he wanted. Be very afraid.