Colgate, Berry Punch, Ditzy Doo and Carrot Top have been friends for a long time. A stallion named the Doctor shows up and Ditzy runs off with him. After Ditzy left, Carrot Top goes into deep depression. Berry Punch is having acholol problems and can't take care of her sisters Berry Pinch and Piña Colada. It's up to Colgate to keep their friendship alive.