The excessive use of the Alicorn amulet has had an unfortunate after-effect on the Great and Powerful Trixie now that she is no longer wearing it, even the smallest uses of her magic causes her body intense pain and crippling migraines as well as being haunted with the guilt her past actions under its influence.

Passing out in front of Ponyville's hospital, she catches the attention of a Nurse Redheart as well as The Doctor both of whom desperately trying to restore her body and her confidence in a trip to the past.