Officer Twilight Sparkle has just woken up in Ponyville's Central Hospital after falling into a coma due to a gun-shot wound from a drunk, idiotic colt, but is shocked and horrified at what she has awoken to…

Equestria, a once beautiful, serene land, has now been ravaged by a disease that turned those infected with it into mindless, undead cannibals. She now has to find her adopted daughter, Scootaloo, and her pet dragon, Spike, among all this mess.

And the dead aren't the only ones to be reckoned with.