Twilight Sparkle wakes up, but from what, she doesn't know.

After a terrifying first encounter with a powerful new enemy with unclear motives, she is thrust into a horrible and unfamiliar world of machines and violence. She has no recollection of her friends, her magic has been broken, and she has no way out

At the same time, her friends are finding troubles all their own: Ponyville in the grip of chaos as a phantom kidnapper causes ponies to vanish, Rainbow Dash lost in an underground maze, Pinkie Pie in the clutches of a serial killer, Fluttershy and Rarity nowhere to be found...

How does all of this tie together? Will they all turn out all right? Does any of this even make sense?