With the population of males dying out in Equestria, the future becomes bleaker by the day. With the tipping point fast approaching, Twilight feels that she has to do something, anything. It is her duty as a Princess to protect the common pony, and with Celestia and Luna unresponsive or otherwise tied up in bureaucracy, she must take drastic measures.

Once the deed is done however, doubt begins creeping up on her. All signs point to the success of the program, but Twilight can't help but think that she might have done the wrong thing.

Fetish Alert:
Transformation, spooge everywhere (eventually) and the blatant wish fulfillment that is HiE, etc.
Anthro tag for good measure, but the only anthro is the human.