The day Derpy Hooves came out of the background, and talked, some human beings didn't estimate it. And she got kicked out of Ponyville. Just because she wasn't like the other ponies. Human beings found her offensive. On a journey to find a new home, Derpy enters a whole new strange world. It's a shock for Derpy - the world is huge!

After the time, she gets to know a real human being herself, and becomes really good friends. But the time always come when you have to say farewell to what you hold dear.