In a humanized Equestria, there is evil lurking in the most unpredictable places. Namely 50 Miles into the desert next to Applelosa.

Fly, a mutant bird/human hybrid, escapes from a genetic engineering lab, and runs for his life, through many small towns and big cities, making friends along the way, and maybe even meeting a girl. Known as 'Subject 60230' by the lab, he is in dire need of help as he runs into the same people in every major city.