In Equestria, a company group that the equivalent of the human world's Bushiroad called BushiPone spread a new card game along with the show on their new invention, gaining great deal of popularity for all of the world, become ponies daily life.
When Sweetie Belle met a colt who gave her, Blaster Blade, she was drawn into the game along with the show's hero, Aichi Sendou, and strives to surpass him. Along with her CMC friends, Spike, and two new ponies friends, Nova Stellar and Light Pulsar, they now aim to tackle Canterlot first Vanguard Fight Championship while at the same time, to learn of becoming a true 'vanguard fighter'.