Twilight Sparkle was crushed when her ancient friend, Discord, snapped. He returned to an old trick and attempted to turn ponies into the opposite of what they were. Twilight, distraught, though not weak, immediately set to work remedying his evils. She once again defeated him, but was left with the unfortunate ponies who had forgotten how to be themselves. Determined to set things straight, she tracked down all of the colour-drained ponies Discord had afflicted, coming finally to a friend whom she had known and travelled with what seemed like aeons ago. After tracking down the Doctor, Twilight now has to confront him and restore the lost personality.