Set in the future, TEW takes place in Equestria, after the downfall of the reign of the Regal Sisters and the evacuation of randomly-selected ponies by the Galactic Republic. Now, Equestria is a wasteland, governed by unwritten laws and blood-thirsty raiders wielding advanced technologies abandoned by the galactic government.

In the year 1105 ANM, a small group of ponies exploring the ruined town of Ponyville will undertake a quest to reunify the Equestrian Kingdom and return the Regal Sisters to the throne of Canterlot, bringing peace and order to the fractured kingdom once more.