There is a bizarre plague sweeping over Equestria. With not an inch of their land safe, Twilight takes her friends to the only safe place left she knows: the world on the other side of the mirror.

But why are the ponies not only allowed to maintain their pony forms this time around, but a certain Equestrian native is also reduced to this form? How will the ponies react to their human counterparts, and what happens when they finally meet two very special human girls?