When the Doctor gets a weak life signal, he later learns it is the Master, an old enemy he thought to be dead. He then finds out that Twilight is needed for what the Master's minions have planned, and it is not good. They plan to resurrect him using a drop of Twilight's blood. Once resurrected, the Master plans to use something the Doctor thought to be lost in time. The Hand of Omega. In the Master's hooves, it could wipe Ponyville off the face of Equestria. The Doctor is not about to let this happen, not one bit. But what will happen when King Sombra teams up with the Master, only to get Twilight?