6 ponies awake to find their stasis pods have been tampered with and their memories have been deleted. Confused and frustrated, they struggle to deal with crimes they do not remember committing and escaping enemies who they don't even know the names of.

Their ship, the Harmony, holds the secrets of their past, and is the only way for them to sail the cosmos to find their future. Whoever they were before, the 6 are determined to find out.