After a biological warfare from the Conversion Bureau, humans has extinct and Equestria was made. In the ruins of L.A., there's one human left in the land of Equestria. As the last human, a man named Morgan Neville must survive everyday in his loneliness lifestyle to avoid any danger awaits him. Even if those danger involves magic colorful ponies trying to kill him to prevent him from decreasing their population and increasing human's population. In hopes to bring humanity back, Morgan must do his best as a scientist to bring humans back to their existence.