From ever since Jason has been living in ponyville, he visited the Ponyville medical care for a check up only once.

He felt really uncomfortable being watched and examined like a strange animal, the humiliation of being touched as they got samples of him was truly disturbing.

He tried to word his complaint, but that was always rejected by the many ponies inside the room. All of them were doctors and nurses that found the human interesting and viewed him as a lifetime opportunity. Even the princesses got along with them and made their own appointments with him.

Sure, it was for science and to see if there was some sort of compatibility between species in case of emergency.

At the end, Jason wished to never visit another doctor as long as he was in Ponyville. The reason was more based on the different body type and the fact that most of the pony medicine was meant for the equines, so the medicine was basically useless for him, except for a minority of them, like aspirin.

That was why he pondered about the pills that were in front of him.

Jason once again read the note that was along the pills.

You have been selected to become a test subject from Foresight laboratories, from the genius mind of Dr. Raziel.

We would be honored for you to become the first one to test our latest product.

Introducing the Booty Pills Body Of Perfection

Inside the box, you receive, along with this note, two bottles containing fifty pills each. One has white pills, and the other one has dark green pills.
These small pills have the unique ability to transform the mass structure of your partner in life, in any way you desire.
All you need to do is consume the white pill while your beloved one has the dark green pill. After that, you have one minute to think on the body and mind you desire your beloved one to have. She can become anything you wish and desire.

Use it with responsibility.

After reading the note, Jason had no words to describe such a thing.

One thing was that magic could do almost anything, but to think that simple pills would do such a thing that not many ponies could do with ease was something to laugh about.

This must truly be some sort of scam made by some prankster, maybe Pinkie Pie, who used to scare him to death when he thought that she did something to his drink, but she only gave him one ice cube.

“This doesn’t seem to be random enough to be a Pinkie Pie prank, and it is too formal to be Rainbow Dash… Could Cherry be the one responsible for this?” he asked to himself, but the idea of that red unicorn passing from jokes to pranks made him shiver in fear.

No, it didn’t seemed to be a prank nor a scam. It all seemed legit and all, but the note had many things that ticked him off about it.

Like the name of the laboratories. He never heard of it here in Ponyville, nor in the pharmacist store. But that could be discarded just by saying that it must be from Manehattan or Fillydelphia. After all, he hadn’t set a foot out of this town.

The other was the name of the doctor. Raziel. That was a strange name for a pony and truly one that he had never heard about. Maybe Twilight would know something about him.

The last thing on the message that was of note was that there seemed to be a strike through in some of the words next to the name of the pills. Jason couldn’t read them well and that gave him a bad vibe about it.

“...Nah. Must be some misspelling there, and they had to scratch it off,” he guessed as he placed the note on the table and took the pills with both of his hands.

At his own conclusion, Jason knew that this was no prank. An unknown pony knows about him and wanted to make him to be a test subject of this strange medicine. That, and there could be a possibility of things going south real quick if the pills fail in the process.

Jason left the two bottles inside the box along with the note and closed it. He knew very well when not to go play with things he didn’t understand.

He then rushed to find the tape and seal the box to return it to his sender. He wanted this out of the way before he could…

A thought crossed in his mind as if a light bulb was turned on in his mind.

The note said that it could change anypony into what he desired, and that could mean to make them humans like him.

The idea made him happy. To finally see another human being made his wild fantasies come to life.

But to find somepony to participate with him was not an easy task.

Jason thought that going to the house of a random pony and asking her to take a green pill and swallow it would be downright crazy.

From the ponies he knew, he had to think of those who could trust him enough to consume a medicine that could be dangerous.

“Who could be crazy enough to help me with this?” Jason pondered on the many ponies that could accept the crazy request.

Jason didn’t need to think of any other mare better qualified to do this than Lyra Heartstrings. She was one of the first mares in the town to see interest in him, and even when she promised to keep her distance from him, she still visited him to have a friendly conversation now and then.

With everything now settled, Jason took the two bottles and reached for the door to go to her house.

“I can make up a story when I get to see her,” he said when he reached the door.

As he opened the door, he noticed a mare in front of it with her hoof held up, ready to knock.

“Oh! Hello, Jason,” said Octavia. She was a little surprised, but she composed herself to talk.

Jason composed himself and smiled at the mare. “Hello, Octavia. Please, come in. Have a seat,” invited Jason, stepping aside for the mare to get inside the house. The mare did so, walking smoothly to sit on the sofa in the living room.

After clearing his throat, Jason decided to begin the conversation, “So, what brings you here?” he asked, trying to be calm and serene.

“I just wanted to spend some time here, since your house is mostly quiet and comfy… and not so annoying,” replied Octavia while she rested her head on the armrest of the sofa.

“So, the same as always,” Jason chuckled while he took a seat next to her.

Octavia began to come at Jason’s house since he invited her to spend the time inside, instead of sleeping in the park, where he found her the first time. Usually, she was there because of her friend and roommate, whom often had to create new beats for the club she works at.

“Well, this time she had this good idea to combine our music styles in her club, and I agreed with her. The concert lasted until the three of the morning, and I barely got any sleep because she began to make her mixes, as always,” complained Octavia, stretching her hooves to relax on the furniture, but she then felt a pang of pain in her head, “and now I have this horrible migraine that is splitting my head in two,” she added while trying to sooth the pain with her hooves.

Jason listened to her complaints and all, but he then felt an idea forming in his head of how to use the pills on Octavia.
“I bet I have some aspirin for you in the bathroom,” he lied as he stood up to go to the mentioned place. “Be right back,” he added as he left the room.

“Thanks Jason, you’re a lifesaver,” thanked Octavia as she relaxed completely on the couch to wait for Jason to return.

From the kitchen, Jason took out the two bottles and opened them to take one pill from each side. The instructions were clear that he needed to consume the white one while Octavia had the green one.

“It would be less suspicious if the one that she consumes would be the white one. Now, I need to convince her to think that the green pill is a new type of aspirin,” he muttered while consuming the white pill and drinking from the glass of water he had prepared.

Jason then walked with the green pill in his hand and a glass of water in the other.

“Here you have it, Octavia, and I know what you’re thinking, why the pill-” Jason’s words were cut off as Octavia snatched the pill and the glass of water from his hands and she swallowed the pill in quick order. “-is... green” he finished with a surprised expression.

“Haa, truly appreciated,” the grey mare said with smile, returning the empty glass to Jason.

“Did you wanted to tell me something?” Octavia then asked.

“No, nothing,” replied Jason rather quickly.

They both remained silent on the couch while Jason felt really nervous of what he had done, but there was no turning back now, since Octavia had consumed the pill. He now needed to think of the body type he wanted Octavia to have.

He began to think of the hairstyle the musician had, including her eye color and voice to start with. Then, he began to focus on her new body type, a gorgeous female body with perfect proportions.

Jason soon was satisfied with how he made the mental image.

That was, until he thought of the migraine the mare had, and with migraine, he thought of aspirins. After that a doctor, and then a nurse. A sexy nurse that resembled the humane Octavia that was in his mind, a clear lustful gaze in her eyes.

“Jason, are you alright?” asked Octavia, interrupting Jason’s train of thoughts, concerned due to his trembling body. “You are sweating a lot” she stated, as she tried to inspect him closely.

How humiliating it was for Jason, to be sweaty when he was nervous. The only way for somepony to discover his lies was when he began to pour sweat like a waterfall.

Thinking on his answer, Jason opened his mouth, only to pause when he noticed the dim light around Octavia’s body, the light increasing its volume as it started to shine like a giant lightbulb.

“What is going on!?” shouted Octavia before disappearing in the brightness.

Jason covered his eyes with his arm to avoid being blinded from the brightness. It seemed that it wouldn’t last for so long. As sudden as the light came, it vanished just as quickly.

The human focused on the room, trying to adjust his eyes from the sudden change of light.
“Octavia, are you alright?” he may be the one that was using the mare for his selfish needs, but that didn’t mean that he wasn’t going to be concerned for her health.

“Yeah, I’m fine,” replied the mare, before she noticed how strange her right forehoof was bending.

Jason was surprised of the result of the transformation the mare has gone through. He expected some slow changes here and there, not a single flash and then the result.

Another thing was that he noticed that the transformation didn’t go as he expected.

Octavia was watching her fingers before examining her arms until they touched her shoulders. She noticed that her muzzle was much smaller, or that she didn’t have one in the first place, but rather, she now had a small nose on her face.
She then trailed her hands to her stomach and onto her waist, continuing to examine her once known hind legs. She was somewhat relieved that she still had hooves.

“What happened?” asked Octavia in a calm tone that took Jason by surprise.

Jason was confused at this point. His first thoughts were why did the pill not change her completely into a human, and why was she so calm about all this?

“I, ugh, well. You see,” Jason had to think of how to respond, but then he saw the mare in front of him tremble, as if she had cold.

The human started to wonder why she was shaking. She seemed to have less fur. That could mean she was more susceptible to cold, or it could be that the grey mare tried to conceal her fears of having another body type.

Taking a few steps forward to check on his friend, Jason had to stop in place as he then noticed the obvious.

Octavia was naked, showing all her body.

Within a second, Jason observed and analyzed the body of the musician. Her impeccable face, her curvaceous chest, those ample hips and her gorgeous thighs.

It was the body that Jason had imagined. Even the smallest detail,if he ever thought about one, was there for him to enjoy.

Octavia bit her lip trying to suppress the burning heat and unreachable itch between her nether regions. But inside her mind, she had a concerned face for the health of the human in front of her, thinking that she was here to give him a check up for his personal appointment.

“Ready got your examination?” asked Octavia with a seductive grin as she took a step toward the human.

Jason was confused at the sudden change of expression of the mare, as he took a step back at the same time Octavia stepped closer. “What do you mean with that?” he asked tumbling down on the sofa.

“Well, as a nurse, I need to make a proper body check up on you,” replied the grey mare as she kneeled in front of him and undoing his pants. “And it would be proper to begin here,” she added, while gazing at his almost awakened member.

Jason was now left with nothing to say. For one, he was confused that the musician he knew since he arrived here was telling him that she was a nurse, and secondly, she was hitting on him.

“It looks in good shape. Now, we have to check if it’s healthy,” and with those words, Octavia pursued her lips onto the tip of Jason’s member.

The hot breath and the feeling of her tongue made his private part go rock hard while he watched her giving him his first blowjob ever.

Octavia sucked his dick with gusto, going down deep to his balls while she reached with her left hand to her own personal place to moisten up her nether regions.

The sweet moans of Octavia made the experience the all more delightful for Jason, as he groaned in approval of her technique.

After a few moments, Jason released his white geyser inside Octavia’s mouth. The musician had to back off, but the next load of cum blew in her face, covering all of it.

“It seems that you truly are a healthy human,” she complimented as she stood up and reclined the chair back while she stood on top of him. “Now, let’s measure this member,” she said as she positioned for the insertion.

Jason had to think hard of what was going on with this situation. Here he was, laying down on the couch, staring at the semi-human naked body of one of his friend while she’s fornicated him talking, like she was a nurse. Delighted about her gorgeous body, he enjoyed observing the work of those pills on her body.

Octavia, for her part, was ecstatic to have this relationship with the human, enjoying the fornication in a body she never knew she could obtain. Even in her new body, many questions filled her mind, but she had to put them aside for now, cause wanted to rut the man like there was no mañana.

Octavia motioned her entire body like a piston on the virile member of the human, enjoying every second of it.

Jason, for his part, felt that he could go on forever, enjoying it more than he ever anticipated. Of course, there were some details, but those are minor compared with the frenzy lust he had.

“Jason I’m about to reach… “ announced Octavia applying more pressure into her pussy, causing the human to reach his own limit.

“So am I!” he replied, releasing his load at the same time the grey mare did. Both cried in pure bliss, overflowing each other with their spunk.

Jason and Octavia were exhausted not having the strength to move from their place. Jason still had many questions in his mind about the pills and the mare, but it could wait until the next morning.

“I love you,” muttered Octavia, pecking a small kiss on the cheek of the sleeping human, joining him in the slumber.

“My… If it wasn’t for my new heart, I might have had a seizure. Ge hi hi hi.” Their secret onlooker laughed, while witnessing the erotic display from the window of Jason’s house. “Stop transmission and send recording to the doctor,” she then said to the metallic orb that recorded the drug’s results.

After a minute, the sphere beeped in a note of completion.
“Excellent. The experiment is going far better than anticipated,” a male voice chuckled from the metallic object while Cherry listened attentively. “Grigory #2 will meet up with the lab rat, so you go and rest for tonight,” he added.

“Understood, Grigory #4 out,” she said. The sphere then dimmed its light and dropped onto her hoof as it was turned off. “Guess I won’t be able to include my routine for the comedy act tomorrow. Ge hi hi hi,” she muttered to herself as she walked back to her home.

Author's Note

So this is how it all begins and I hope this pleases all of you.

Maybe next time I'll be more descriptive with these scenes.