For as long as anyone has known her, Scootaloo has been a normal, although rather energetic child. She lives with her adopted mother in National City and has known her best friends Sweetie Belle and Apple Bloom since they were all in Middle School.

But Scootaloo has a secret that she's been keeping for years, that she's not of this earth, something she can't even tell her best friends about. As the three of them start college though, an accident happens that forces her to choose between telling her friends the truth or letting them die, and she chooses to tell them.

Now revealed to be the last daughter of a dead world, Scootaloo must defend her new home from threats from both within and without while trying to figure out what to do with her life.

Crossover with DC Comics' Supergirl.