Johnny Test is the furthest thing possible from the average 10 year old boy:

He has a talking dog, battles villains, saved the world a couple of times, and has an alien girlfriend. However, his biggest abnormality is that his sisters are geniuses and use him to test their experiments. One day he finds out they, and his dog Dukey, are bronies and laughs at them. One thing is known:

NEVER piss off a sibling who can get even with revenge