This is something that came to me when I saw the episode for Vasto Lorde Ichigo.

When Ichigo loses the fight against Ulqiorra he is transported to Equestria where he runs into Twilight, who was getting kidnapped at the time. He somehow mistakes her voice for Orihime's and protects her.

Now after being saved by him Twilight has to make sure to keep him in check as she had already witnessed some of his power. How well will these two get along and what does this mean for Twilight's future and the safety of her friends and family, and all of Equestria.

Contains spoilers for Bleach.