(Protagonist is female, and I decided to name her similar to Makoto Yuki, the name of the P3 MC in the anime, since the FMC isn't canon.)

24-year-old Mikata Yuki (結城三方) saved the world from Nyx 7 years prior (2010 in-game). Now, after all her friends have fully recovered from the madness, and all have graduated, she decides to move to the more quaint town of Ponyville to escape Tatsumi Port Island, where her parents died in an incident 17 years prior. But, when she arrives, another incident, similar to the Dark Hour, but somewhat different, occurs. Now, uniting with Yu Narukami (鳴上 悠) and his Inaba Investigation Team, they try to save the world yet again.

Honestly, though. Trouble seems to follow me wherever I go.

End of game spoilers for Persona 3 (kinda)

Persona 4 Spoilers

Events after S8 Premire

Kinda like Persona Q: Shadow of the Labyrinth

Persona 4 Arena/Arena Ultimax/BlazBlue: Cross Tag Battle (is this even canon?) didn't happen here.

Atlus/SEGA © Shin Megami Tense: Persona 3 Portable, Persona 4 Golden, Persona Q: Shadow of the Labyrinth
Hasbro © My Little Pony: Friendship is Magic