A strange virus that turns ponies into zombies is haunting the citizens of Ponyville when Twilight and Spike wake up. They decide to fight their way trough the town, team up with their friends and use the Elements of Harmony to stop the infection and the bloody horror it brought over the town. Will the ponies be able to survive in a rioting and chaotic Ponyville, get to the Elements of Harmony and free their precious town?