Twilight meets her friends for the first time by order of her mentor, Celestia. The solar princess then managed to save her sister with the help of Twilight and her new friends. Together, they managed to restore peace to Equestria for a time.

But as anybody would know, that kind of time usually never lasts for very long. Now they do their best to both be the protectors of their land and to learn to live their day-to-day lives. Unfortunately for them, they meet a new threat that desires to transform Equestria into a totalitarian industrial utopia in his own image.

Now with Equestria on the line, the doctor must be stopped whenever he enacts one of his many schemes.