After venturing into the dark unknown to help save a poor abused girl from a religious zealous cult, the Mane Six and Spike are back again to venture into the Multiverse. Accompanied by Countess Coloratura, down on her luck after harsh comments from musical critics who believe her time has passed by, they venture into a magical world of mystery, music, and excitement.

Finding themselves in New York City in the year 1841, they meet a laid off entrepreneur named P.T Barnum who has a genius idea to put together a spectacular show to which the likes of man had never seen. On the way they will encounter much criticism from others, but a wise man once said,

"No one ever made a difference by being like everyone else"