"So, Minuette..." Lyra said. "What's your expert diagnosis?"

Minuette sighed. "I'm sorry, Lyra," she said. "But that tooth is rotten; I'm going to have to take it out immediately."

"Oh." Lyra's face fell. "Oh dear."

Minuette reached out and gave her a sympathetic pat. "Would you like a general anaesthetic to put you to sleep during the procedure?" she asked. "It'll cost you a little bit more, but most ponies prefer it to a local anaesthetic."

Lyra nodded. "Yes, please," she replied. "Last time I had a local anaesthetic, it took a while to work, and I felt everything."

Minuette grimaced. "That will not happen to you here," she said, applying a mask over Lyra's muzzle. "Just relax, count backwards from ten, and it'll be over before you know it."

"All right." Lyra closed her eyes as Minuette turned a valve. "Ten, nine, eight... seven... six..." Her world faded into blackness as the anaesthetic took its toll, allowing sleep to claim her.

Lyra's eyes shot open. Looking around, she could see that she was standing in the middle of Ponyville.

Moments later, she came to the sudden and terrible realisation that she was the only pony in the whole town.

Author's Note

So it begins.

Why Minuette and Lyra? Well, I wasn't sure which characters to use, so I went to Derpibooru and pressed 'Random Image.' Twilight was the first result, but since I used her to start the story for The One Hundred Words Collab, I pressed it again and got Minuette. I then pressed the button until I got to another background pony, and that led me to Lyra.

Trust me, it's only going to get more random from here.