After Pinkie goes to Canterlot hospital for treatment of an illness and misses the premiere of a movie she's been waiting to see, the others decide to reenact it for her in her hospital room! Only to discover that ghosts don't only exist in movies. As the Elements of Harmony, they must protect Equestria from threats both of this world, and the next. Join Twilight, Applejack, Rarity, Rainbow and Fluttershy as they battle a host of ghouls and their evil leader released from their eternal prison.

Consider this a re-imagining of Ghostbusters. It's not an exact copy except with ponies, but a few memorable and funny scenes will be reenacted via our favorite ponies.