The Doctor has been running his whole life. He has ran from the death of Gallopfray, the guilt that has followed him all his life, and even his name, but has he also ran from love? Well not anymore.
I intentionally did not choose someone specific for The Doctor to be paired with that's up to you. If you want to pair him with anypony,Ex. Twilight, Derpy, Octavia, etc., if that makes you happy go on ahead.