It has been 1000 years since the regal sisters mysteriously vanished. The world has changed. Queen Trixie's forces march east, plunging the world into war on a massive scale. Six ponies from six worlds will meet. They must change the world.

The first report of a suicide in Equestria in over a century. What could have caused this? Twilight Sparkle investigates to find the truth, uncovering a conspiracy hidden between a web of lies and deceit.

After the destruction of Ponyville, the mane 6 embark on a quest of revenge and self discovery.