A spell that Twilight had been yearning to cast ever since she arrived in Ponyville goes awry leaving Spike without his memory

Spike is rejected by Rarity for the last time. His mood goes sour and only one unicorn can help him

After Spike loses Twilight, Rarity is concerned for his well-being. She visits him and is shocked to find that he might need more than a gift or two to help him.