What would happen if Edward Elric, Sonic, John 117, Deadpool, Isaac Clarke, and Luke Skywalker had help defeat Nightmare Moon and Mephiles the Dark and created the Elements of Alchemy, Encouragement, Justice, Heroism, Altruistic, and Hope?

The Elements of Insanity has teamed up with Dr. Eggman, Gray Mann, and Discord to take over Earth, Mobius, and Equestria by merging them together and R.E.D. team, Mane 6, Sonic and his friends must stop them.