The Mane 6 and Violette Rainbow reunite with their Golden Retriever pals, the Buddies, in order to head to Egypt to rescue Mudbud's owner Pete, his grandpa, a young zebra filly named Skye and her mother Mariama from a hairless cat's wicked plans.

The Mane 6 reunites with Mystery Incorporated and a band of new friends, to solve an intergalactic mystery on the moon, and save a maiden space voyage from a terrifying alien, all while trying to demonstrate the true meaning of friendship.

The Mane 6, Allura and Twitch venture to the city of Los Angeles to help a crew of five criminal animals and their five young tiger trainees try to reform and become better people... unaware of another, more devious plot lurking in the background.

After deducing some intense information about Sunny's mother and the alicorn realm of Skyros, the Mane 6 reunites with Mystery Inc and some new friends in order to solve the mystery of a curse surrounding Cleopatra’s tomb in the deserts of Egypt.

In the fourth season opener, the Mane 6 venture to Piqua, Ohio to help three best friends deal with their horrible principal by hypnotizing him into a dimwitted superhero while trying to stop Allura's brother Alterro and his new partners' evil plans.

In the season three finale, the Mane 6 go up against Allura and Twitch once more while trying to help a young idealistic teenager named Asha save her kingdom of Rosas from them and the evil King Magnifico and save the citizens' wishes.

The Mane 6 reunite with Rudolph, Borealis and all their North Pole friends, as well as meet some new friends, including Borealis' long-lost mother, to save all the toys from the evil Toy Taker, who wants to end Christmas forever.

The Mane 6 reunite with their Bikini Bottom friends, but not long after arriving, they must help SpongeBob, Tropic, Sandy and Volcano, along with Sandy's family, save Bikini Bottom and all their friends from Allura and a greedy CEO's plans.

The Mane 6 and the Pippsqueaks journey back to Fernfield to help the Buddies, their kids and some new friends defeat an evil warlock and the Howlloween Hound from opening the portal to the netherworld, letting its spirits remain in Fernfield forever.

Ruby Jubilee and the Dreamlands go on their first Unity Quest with the Mane 6, in order to help Mystery Incorporated sing and dance their way through a vampire mystery in the bayous of Louisiana.

Our pony heroes are transported into Robert Louis Stevenson's classic pirate tale, and are reunited with some of their Muppet friends for a high-stakes adventure on the high seas to protect a special treasure from a band of pirates.

The Mane 6 and Sparky must help Shaggy (changed into a werewolf), Scooby, Scrappy and Shaggy’s girlfriend Googie escape Transylvania and Count Dracula by winning the Monster Road Rally, and help some flying leopards reclaim their freedom as well.

The Mane 6 and Sparky head back to Cartoon World and become superheroes once again in order to help their friends defeat the evil Vetvix, who plans on using a dangerous cosmic weapon to enslave the universe.

The Mane 6 take the Pippsqueaks on their latest Unity Quest to Fernfield, which goes galactic as they, the Pippsqueaks and the Buddies are accidentally launched into space, and now they must get themselves and some new friends of theirs home.

The Mane 6’s latest adventure with Mystery Incorporated will take them into cyber-space to take on a dastardly computer virus, where they, along with a new wolf friend trying to find her sister, must leap through different levels to return home.