When Spike is accidentally given cosmic power and goes a little nuts as a result, he is trapped in a magic lamp and sent hurdling into the past, forced to grant the wishes of the one who holds the lamp Spike goes on a grand adventure to get back home

The Mane 6 leave Equestria for 10 years and come back to a different world

The CMC,Babs seed, Silver Spoon, and Spike are turned into monsters by dark magic

Rarity noticed Spike is seeing her less and less and is worried somepony else may have captured his heart, Vinyl notices that Octavia is around less and less and is worried she's out growing her.

Nightmare Spike tries to deal with Flurry heart

Sweetie Bot is forced into battle with Spike, who has been turned into a Living Glitch

20 years ago a magical catastrophe turned the world of Equestria into a world of endless sky and floating islands, to protect as much of Equestria as they could the 4 princesses encased what was left in a shield. many where lost, saved ,and cursed.

Spike's bed isn't the most comfirtable thing and in an attempt to find a better place to sleep he ends up sleep walking and using his friends as beds to find the most comfortable one.

A man wakes up in Equestria as Peridot, he is then forced to go and find an item of power for the one who summoned him if he ever want to go home, and to make thing worse he has to do it while also fleeing from a pink pony determined to befriend him

With the beginning of Winter comes a lot of snow related joys, but for Fluttershy it was just a sign that all her Animals friends would be sleeping for a few months she was content to just solder through it then she realized Ponies can pet Dragons

Scootaloo Leave's Ponyville with Two Friends, their just not the friend's you'd expect

When the Zombie Apocalypse begins Spike and Trixie end up teleported outside of Equestria and must now make their way to the Crystal Empire. Starlight and Twilight go on a series of adventures saving survivors and searching for Spike and Trixie

Luna goes to Ponyville and proceeds to try and Court Spike

Spike accidentaly gains the affections of Songbird Serenade

Trixie and Spike use a pair of magical ear-rings to fuse into a Powerful being with dangerous powers and side effects.