Blessed with immortality. Having the ability to live along side your friends and family without worrying whether or not you might pass before them one day. Some would find this to be a....blessing. But what if you see things differently?
Twilight Sparkle does. Being able to live forever means nothing if she can't be with her friends, so how will she be able to cope when she is left without a single one of her friends to be by her side?
The last one she saw go was especially hard for her to see leave. Now Twilight is left with nopony by her side and how can she live on without at least one of them?

Live with me forever, Pinkie.....