Her library has been demolished and replaced with a tacky, fragile mess of crystals that vaguely resembles a tree housing several large rooms. Twilight is constantly getting lost. Even worse, Spike is constantly devouring small areas of this new "castle".
The Elements have been replaced by a freakish effect that falls over her friends and her whenever they instinctively reach out for their "harmonic traits" – which they are doing less and less.
Life is boring. There is no need for any source of protection, as attacks on Equestria have become all but extinct.
Rainbow Dash has become even more easily agitated and self-centered. Pinkie Pie has become lost and never smiles. Fluttershy has stopped caring for her animals, friends, and self. Applejack has become frail in both figure and attitude. Rarity is keeping money to herself, never spending it.
Twilight decides that the world must burn.