Set in Equestria, No Compromise is a story of a pony with a idea. Fighting for his dream of making genetic modification a possibility, this pony will not give into the word of those who surround him, and he will not let his dream be brought down by others. Howard Galt will face of with society and the group, “The Children of Natural Order," who wish to keep everyone equal and not to mess with the natural order of the world.

As I said in the short description, This story follows Ayn Rand's philosophy ,objectivism, which she described in this quote, "My philosophy, in essence, is the concept of man as a heroic being, with his own happiness as the moral purpose of his life, with productive achievement as his noblest activity, and reason as his only absolute.
—Ayn Rand, Atlas Shrugged"

And uses the Science theme of Bioshock ,genetic modification, as a story of stuggle against the opinion of pure and proud.

Also I could not find a suitable image