This story follows Twilight as she falls into paranoia, trying to keep her kingdom of Ponyville safe from infections. Such as the “feather flu” as well as many others that could quickly affect the respiratory system or the bloodstream. Sending them to Ponyville Hospital for distribution.

Soon enough she begins to make certain illnesses and experiment on animals to see if she can cure them before the illnesses become fatal.
The paranoia continues to persist, Twilight descending into madness as she tries to make vaccinations for illnesses that COULD exist.

Soon the mane 6 begins to vanish 1 by 1.
What happened to them? Where will this story go, lets find out!

Authors note: This story series is an Alternate universe that i made back in 2020. Which I then edited, expanded and polished up in Jan 2024. I hope you guys enjoy the journey as the story progresses. The story also contains personal head canons from the canon show.
Any and all questions of the story will be answered in the comments :D