According to the MSPA wiki, the etymology of the word kismesis stems from the combination of the word "kismet" (loosely meaning fate or soulmate), and the Greek goddess "Nemesis".

The concept of a kismesissitude (or to the average person who doesn't wanna say that every time, a blackrom) is one that hasn't graced the Equestrian multiverse a lot. But recently, one universe, touched by the blight of a narrative not unlike Homestuck, has seen a blackrom blossom between the mercenary ex-queen of the hive, and an intense blood god from a dead narrative.

Will they be able to keep their strange relationship professional in the workplace, or will their explosive love-rivalry have disastrous consequences for the ponies, the people, the universe, and the concept of love?