A disease has come about in Equestria wiping out every male of every species in under five years. With no way to repopulate Equestria, Celestia must look elsewhere for the solution to Equestria's problem. Finding out that a human is the only way to repopulate Equestria, Celestia must convince the Human to aid in the re-population of Equestria.

Inspiration: The Comic Series "Y: The Last Man" even though I only know the premise and never actually read it and " Into a New World" by Poodicus