The girls become worried when they notice something is wrong with Applejack. On her side, Applejack has to deal with something from her past that still haunt her family.

The mane 6 are on a mission. A mission to vaccinate Pinkie Pie and they won't stop until they completed it. For her sake.

Applejack and Rainbow Dash have a sleepover during which an injury lead the girls to talk about their relationship and later share an intimate moment.