After a shocking turn of events involving Opaline, the ponies return to Acme Falls for a new mission with the Animaniacs cast... and this mission is crucial, for Opaline is a huge threat in Warnerstock, and secrets must be released to stop her plans.

On their second Unity Quest, the Mane 5 and Misty meet Mystery Incorporated for the first time and help them solve a caper on Moonscar Island going back over 200 years... all while Opaline lurks in the shadows with her own scheme in mind.

After a strange spell is cast by the Unity Crystals, the Mane 5 and Misty must help the Warner Siblings retrieve a magical wishing star from a greedy king and save the kingdom of Warnerstock from poverty.

Ever wonder what would happen if the ponies of Make Your Mark met up with the cast of Amphibia? Tune into this epic crossover series in order to find out!